Antibacterial agent 156

Antibacterial Agent 156 (Compound 57) is a bactericidal small molecule that selectively inhibits Clostridioides difficile cell wall synthesis. It exhibits potent in vitro activity, with MIC50 and MIC90 values of 0.5 μg/mL and 1 μg/mL, respectively, against a panel of 101 strains. This agent is a valuable research tool for studying novel antibiotic mechanisms and C. difficile pathogenesis.