MAPK-IN-2
MAPK-IN-2 is a potent multi-kinase inhibitor targeting key oncogenic drivers including EGFR, B-RAF, c-MET, and CDK4/6. It demonstrates strong anti-proliferative activity in vitro against various cancer cell lines, particularly those harboring EGFR T790M and B-RAF V600E mutations, making it a valuable tool for cancer signaling pathway research.
Product Specifications
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
ClC1=CC=C (C (C=C (C2=CNC3=C2C=CC=C3) N4) =C (C#N) C4=O) C (Cl) =C1
Molecular Formula
C20H11Cl2N3O
Molecular Weight
380.23
Storage Conditions
-20°C
Notes
For research use only.
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