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EGFR/CDK2-IN-4

EGFR/CDK2-IN-4 is a dual-targeting inhibitor with IC50 values of 89.6 nM for EGFR and 165.4 nM for CDK2. It exhibits anti-proliferative activity in MCF-7 breast cancer cells (IC50 = 2.74 μM) by inducing S-phase cell cycle arrest and apoptosis, making it a useful tool for oncology research in vitro.

Product Specifications

Field of Research

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin; Cell Biology, Signal Transduction

Molecular Formula

C24H16N6OS2

Molecular Weight

468.55

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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