Pan-KRAS-IN-4
Pan-KRAS-IN-4 is a highly potent small molecule inhibitor targeting KRAS mutations, with IC50 values of 0.37 nM against G12C and 0.19 nM against G12V. This compound is a valuable research tool for investigating KRAS-driven cancers in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2885961-55-5
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
C (#C) C=1C=2C (=CC (O) =CC2C=CC1F) C3=C (F) C4=C (C=N3) C (=NC (OCC56N (CCC5) CCC6) =N4) N7CC8N (C (C=C) =O) C (C7) CC8
Molecular Formula
C36H34F2N6O3
Molecular Weight
636.69
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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