DL-Norvaline

DL-Norvaline, a derivative of L-norvaline, L-norvaline is a non-competitive inhibitor of arginase.

Product Specifications

CAS Number

[760-78-1]

Product Name Alternative

2-Aminopentanoic acid

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Arginase; Endogenous Metabolite

Type

Natural Products

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/DL-Norvaline.html

Purity

98.0

Solubility

10 mM in DMSO|H2O : 50 mg/mL (ultrasonic)

Smiles

CCCC(N)C(O)=O

Molecular Formula

C5H11NO2

Molecular Weight

117.15

Precautions

H302, H315, H319, H335

References & Citations

[1]Sosroseno W, et al. Arginase activity in a murine macrophage cell line (RAW264.7) stimulated with lipopolysaccharide from Actinobacillus actinomycetemcomitans. Oral Microbiol Immunol. 2006 Jun;21 (3) :145-50.|[2]El-Bassossy HM, et al. Arginase inhibition alleviates hypertension associated with diabetes: effect on endothelial dependent relaxation and NO production. Vascul Pharmacol. 2012 Nov-Dec;57 (5-6) :194-200.