DL-Norvaline
DL-Norvaline, a derivative of L-norvaline, L-norvaline is a non-competitive inhibitor of arginase.
Product Specifications
CAS Number
[760-78-1]
Product Name Alternative
2-Aminopentanoic acid
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Arginase; Endogenous Metabolite
Type
Natural Products
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/DL-Norvaline.html
Purity
98.0
Solubility
10 mM in DMSO|H2O : 50 mg/mL (ultrasonic)
Smiles
CCCC(N)C(O)=O
Molecular Formula
C5H11NO2
Molecular Weight
117.15
Precautions
H302, H315, H319, H335
References & Citations
[1]Sosroseno W, et al. Arginase activity in a murine macrophage cell line (RAW264.7) stimulated with lipopolysaccharide from Actinobacillus actinomycetemcomitans. Oral Microbiol Immunol. 2006 Jun;21 (3) :145-50.|[2]El-Bassossy HM, et al. Arginase inhibition alleviates hypertension associated with diabetes: effect on endothelial dependent relaxation and NO production. Vascul Pharmacol. 2012 Nov-Dec;57 (5-6) :194-200.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
Available Sizes
Curated Selection
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