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NPI52

NPI52 (Compound E1) is a potent small-molecule inhibitor of the foot-and-mouth disease virus 3C protease (FMDV 3Cpro) . It demonstrates inhibitory activity with IC50 values of 0.05 μM in vitro (FRET) and 0.11 μM in cell-based assays, supporting its use in antiviral research targeting picornavirus replication.

Product Specifications

CAS Number

1429218-68-7

Field of Research

Infectious Disease & Virology

Smiles

C ([C@@H] (C (N[C@H] (C (N[C@@H] (C[C@@H]1CCNC1=O) C=O) =O) CC (C) C) =O) NC (OCC2=CC=CC=C2) =O) C=3C4=C (C=CC3) C=CC=C4

Molecular Formula

C34H40N4O6

Molecular Weight

600.7

Storage Conditions

-20°C

Notes

For research use only.

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