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ORIC-533

ORIC-533 is an orally bioavailable, competitive CD73 inhibitor that reactivates suppressed CD8+ T cells. It demonstrates potent anti-multiple myeloma activity by inducing tumor cell lysis within the bone marrow niche, as shown in preclinical in vitro and in vivo studies.

Product Specifications

CAS Number

2641306-62-7

Field of Research

Immunology & Inflammation

Smiles

O[C@H]1[C@H] (N2C=3C (C=N2) =C (NC4CCCC4) N=C (Cl) N3) O[C@H] (CO[C@] (COCC=5NN=NN5) (P (=O) (O) O) CO) [C@H]1O

Molecular Formula

C20H29ClN9O9P

Molecular Weight

605.93

Storage Conditions

-20°C

Notes

For research use only.

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