PHGDH-IN-5
PHGDH-IN-5 (Compound B12) is a potent covalent PHGDH inhibitor with an IC50 of 0.29 μM. It suppresses serine biosynthesis from glucose and inhibits proliferation in PHGDH-overexpressing cancer cell lines, making it a valuable tool for studying cancer metabolism in vitro.
Product Specifications
CAS Number
17402-86-7
Field of Research
Metabolism Research
Smiles
N (=O) (=O) C1=C2C (S (=O) (=O) C=C2) =CC=C1
Molecular Formula
C8H5NO4S
Molecular Weight
211.20
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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