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PHGDH-IN-5

PHGDH-IN-5 (Compound B12) is a potent covalent PHGDH inhibitor with an IC50 of 0.29 μM. It suppresses serine biosynthesis from glucose and inhibits proliferation in PHGDH-overexpressing cancer cell lines, making it a valuable tool for studying cancer metabolism in vitro.

Product Specifications

CAS Number

17402-86-7

Field of Research

Metabolism Research

Smiles

N (=O) (=O) C1=C2C (S (=O) (=O) C=C2) =CC=C1

Molecular Formula

C8H5NO4S

Molecular Weight

211.20

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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