Trimetazidine-N-oxide

Trimetazidine-N-oxide, the primary active metabolite of Trimetazidine, acts as a potent and selective inhibitor of long-chain 3-ketoacyl-CoA thiolase (IC50: 75 nM) . This small molecule exhibits antioxidant, anti-inflammatory, and gastroprotective activities, supporting its use in cardiovascular and metabolic research involving both in vitro enzyme assays and in vivo models.