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β-Amanitin

β-Amanitin is a potent cyclic peptide toxin from the death cap mushroom that selectively inhibits eukaryotic RNA polymerases II and III. It is widely used in molecular biology research to study transcription mechanisms, regulate gene expression in vitro, and has been employed in vivo to model hepatotoxicity.

Product Specifications

CAS Number

21150-22-1

Field of Research

Cell Biology, Molecular Biology

Smiles

[H][C@@]12C[C@@H] (O) CN1C (=O) [C@] ([H]) (CC (O) =O) NC (=O) [C@]1 ([H]) C[S@] (=O) c3[nH]c4cc (O) ccc4c3C[C@] ([H]) (NC (=O) [C@@] ([H]) (NC2=O) [C@@H] (C) [C@@H] (O) CO) C (=O) NCC (=O) N[C@@] ([H]) ([C@@H] (C) CC) C (=O) NCC (=O) N1

Molecular Formula

C39H53N9O15S

Molecular Weight

919.96

Storage Conditions

-20°C

Notes

For research use only.

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