ARD-266
ARD-266 is a VHL-based PROTAC that induces the degradation of androgen receptor (AR) proteins. It is a research tool for investigating AR-dependent pathways and has demonstrated activity in both in vitro and in vivo models of prostate cancer.
Product Specifications
CAS Number
2666951-70-6
Product Name Alternative
ARD266, ARD-266, ARD 266, VHL
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
99.89% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:5 mg/mL (5.46 mM) ; DMSO:80 mg/mL (87.38 mM)
Smiles
O ([C@@H]1C (C) (C) [C@@H] (NC (=O) C2=CC=C (C#CC3CCN (C (C[C@H] (NC (=O) [C@H]4N (C ([C@H] ([C@H] (C) C) C=5ON=C (C) C5) =O) C[C@H] (O) C4) C6=CC=CC=C6) =O) CC3) C=C2) C1 (C) C) C7=CC (Cl) =C (C#N) C=C7
Molecular Formula
C52H59ClN6O7
Molecular Weight
915.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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