DMEA-PNU-159682
DMEA-PNU-159682 (D12) is a cytotoxic small molecule derived from the neomycin metabolite MMDX and is the active warhead of antibody-drug conjugates (ADCs) . It is a potent DNA-alkylating agent used in cancer research, demonstrating efficacy in both in vitro cytotoxicity assays and in vivo tumor model studies.
Product Specifications
CAS Number
1799421-48-9
Smiles
O ([C@@H]1C2=C (C (O) =C3C (=C2O) C (=O) C=4C (C3=O) =CC=CC4OC) C[C@] (C (COC (N (CCNC) C) =O) =O) (O) C1) [C@H]5C[C@@]6 (N7[C@] (O[C@@]6 ([C@H] (C) O5) [H]) ([C@@H] (OC) OCC7) [H]) [H]
Molecular Formula
C37H45N3O14
Molecular Weight
755.76
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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