PROTAC IRAK4 degrader-1
PROTAC IRAK4 degrader-1 (I-210) is a heterobifunctional degrader that links an IRAK4-targeting ligand to the Cereblon recruiter Pomalidomide via an AM-Imidazole-PA-Boc linker. This compound facilitates the targeted ubiquitination and proteasomal degradation of IRAK4, serving as a valuable chemical probe for studying IRAK4 biology and oncology research in cellular models.
Product Specifications
CAS Number
2360533-90-8
Product Name Alternative
PROTAC IRAK4 degrader1, PROTAC IRAK-4 degrader-1, PROTAC IRAK4 degrader-1, PROTAC IRAK4 degrader 1
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.76% (May vary between batches)
Solubility
DMSO:160 mg/mL (176.82 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (5.53 mM)
Smiles
Molecular Formula
C44H39F3N12O7
Molecular Weight
904.85
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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