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BnO-PEG1-CH2CO2tBu

BnO-PEG1-CH2CO2tBu is a PROTAC linker used to conjugate a target-binding ligand to an E3 ligase ligand, enabling targeted protein degradation via the ubiquitin-proteasome system. This PEG-based spacer is utilized in both in vitro and in vivo PROTAC development for probing disease-related protein functions.

Product Specifications

CAS Number

1309451-06-6

Field of Research

Cell Biology, Pharmacology & Drug Discovery

Smiles

CC (C) (C) OC (=O) COCCOCc1ccccc1

Molecular Formula

C15H22O4

Molecular Weight

266.33

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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RPA2 (RPA32, 60S acidic ribosomal protein P1, AA409079, AI325195, AU020965, HSSB, ik:tdsubc_2g1, M (2) 21C, MGC137236, OTTHUMP00000004008, p32, p34, RCJMB04_6d17 replication protein A2, 32kD, REPA 2, REPA1, REPA2, Replication factor A protein 2, Replication protein A 32kD subunit, Replication protein A 32kD subunit, Replication protein A 34kD subunit, Replication protein A, replication protein A1 (70kD), Replication Protein A2 (32kD), Replication protein A2 32kD, Replication protein A2 32kD, Replication protein A2, Replication protein A2, 32kD, RF-A protein 2, Rf-A2, RFA, RFA2_HUMAN, RP A, RP-A p32, RP-A p34, RP21C, RPA 2, RPA 32, RPA, RPA2, RPA32, RPA34, RPA70, RpLP1, RpP2, xx:tdsubc_2g1, zgc:109822)
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RPA2 (RPA32, 60S acidic ribosomal protein P1, AA409079, AI325195, AU020965, HSSB, ik:tdsubc_2g1, M (2) 21C, MGC137236, OTTHUMP00000004008, p32, p34, RCJMB04_6d17 replication protein A2, 32kD, REPA 2, REPA1, REPA2, Replication factor A protein 2, Replication protein A 32kD subunit, Replication protein A 32kD subunit, Replication protein A 34kD subunit, Replication protein A, replication protein A1 (70kD), Replication Protein A2 (32kD), Replication protein A2 32kD, Replication protein A2 32kD, Replication protein A2, Replication protein A2, 32kD, RF-A protein 2, Rf-A2, RFA, RFA2_HUMAN, RP A, RP-A p32, RP-A p34, RP21C, RPA 2, RPA 32, RPA, RPA2, RPA32, RPA34, RPA70, RpLP1, RpP2, xx:tdsubc_2g1, zgc:109822)

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