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DBCO-NHCO-PEG5-NHS ester

This heterobifunctional PEG linker, featuring DBCO and NHS ester groups, is designed for PROTAC synthesis. It enables the conjugation of targeting ligands to E3 ligase binders via bioorthogonal click chemistry, facilitating the construction of molecules for targeted protein degradation studies in both cellular and biochemical assays.

Product Specifications

CAS Number

1378531-80-6

Field of Research

Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Smiles

O=C (ON1C (=O) CCC1=O) CCOCCOCCOCCOCCOCCC (=O) NCCC (=O) N2C=3C=CC=CC3C#CC=4C=CC=CC4C2

Molecular Formula

C36H43N3O11

Molecular Weight

693.74

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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