DNP-PEG4-NHS ester
DNP-PEG4-NHS ester is a heterobifunctional linker used in constructing PROTAC molecules for targeted protein degradation research. Its PEG spacer and NHS ester group facilitate the synthesis of cell-permeable PROTACs, enabling both in vitro biochemical studies and in vivo proof-of-concept experiments in disease models.
Product Specifications
CAS Number
858126-78-0
Product Name Alternative
DNPPEG4NHS ester
Field of Research
Pharmacology & Drug Discovery
Purity
99.77% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble) ; DMSO:≥ 80 mg/mL;10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (6.24 mM)
Smiles
O=C (CCOCCOCCOCCOCCNC1=CC=C ([N+] ([O-]) =O) C=C1[N+] ([O-]) =O) ON2C (CCC2=O) =O
Molecular Formula
C21H28N4O12
Molecular Weight
528.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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