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DNP-PEG4-NHS ester

DNP-PEG4-NHS ester is a heterobifunctional linker used in constructing PROTAC molecules for targeted protein degradation research. Its PEG spacer and NHS ester group facilitate the synthesis of cell-permeable PROTACs, enabling both in vitro biochemical studies and in vivo proof-of-concept experiments in disease models.

Product Specifications

CAS Number

858126-78-0

Product Name Alternative

DNPPEG4NHS ester

Field of Research

Pharmacology & Drug Discovery

Purity

99.77% (May vary between batches)

Solubility

H2O:< 1 mg/mL (insoluble) ; DMSO:≥ 80 mg/mL;10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (6.24 mM)

Smiles

O=C (CCOCCOCCOCCOCCNC1=CC=C ([N+] ([O-]) =O) C=C1[N+] ([O-]) =O) ON2C (CCC2=O) =O

Molecular Formula

C21H28N4O12

Molecular Weight

528.47

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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