FR167344 free base
FR167344 free base is a potent, orally bioavailable, and selective nonpeptide antagonist of the bradykinin B2 receptor, with an IC50 of 65 nM and no significant affinity for the B1 subtype. It is a valuable research tool for investigating the role of B2 receptors in inflammation, pain, and vascular permeability in both in vitro and in vivo models.
Product Specifications
CAS Number
215258-13-2
Field of Research
Pharmacology & Drug Discovery
Smiles
O (CC1=C (Cl) C (N (C (CNC (/C=C/C2=CC=C (C (N (C) C) =O) C=C2) =O) =O) C) =CC=C1Cl) C=3C=4N (C (Br) =C (C) N4) C=CC3
Molecular Formula
C30H28BrCl2N5O4
Molecular Weight
673.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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