HO-PEG20-OH
HO-PEG20-OH is a polyethylene glycol (PEG) spacer used to construct PROTAC molecules, connecting a target-binding ligand to an E3 ligase recruiter. This linker facilitates the ubiquitination and subsequent proteasomal degradation of specific proteins, a mechanism applied in both cellular and preclinical in vivo studies for targeted protein degradation research.
Product Specifications
CAS Number
351342-08-0
Field of Research
Pharmacology & Drug Discovery
Smiles
OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
Molecular Formula
C40H82O21
Molecular Weight
899.07
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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