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Mal-amido-PEG2-TFP ester

Mal-amido-PEG2-TFP ester is a heterobifunctional linker featuring an amide group and a TFP ester, connected by a short polyethylene glycol (PEG) spacer. It is widely used in chemical biology, particularly for constructing PROTAC molecules in both in vitro and cellular degradation studies to facilitate targeted protein removal.

Product Specifications

CAS Number

1431291-44-9

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Smiles

O=C (OC=1C (F) =C (F) C=C (F) C1F) CCOCCOCCNC (=O) CCN2C (=O) C=CC2=O

Molecular Formula

C20H20F4N2O7

Molecular Weight

476.38

Storage Conditions

-20°C

Notes

For research use only.

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