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MC-GGFG-DX8951

MC-GGFG-DX8951 is an antibody-drug conjugate (ADC) featuring the potent topoisomerase I inhibitor DX8951 linked via a cleavable GGFG peptide. This conjugate is designed for targeted cancer therapy research and has demonstrated antitumor activity in both in vitro and in vivo preclinical studies.

Product Specifications

CAS Number

1600418-29-8

Product Name Alternative

Camptothecins, DrugLinker Conjugates for ADC, DrugLinkerConjugatesforADC, MC GGFG DX8951, MC-GGFG-DX 8951, MCGGFGDX8951, MC-GGFG-DX8951, MC-GGFG-DX-8951, MC-GGFG-Exatecan

Field of Research

Molecular Biology, Pharmacology & Drug Discovery

Purity

99.04% (May vary between batches)

Solubility

DMSO:40 mg/mL (42.24 mM)

Smiles

N (C (CNC ([C@H] (CC1=CC=CC=C1) NC (CNC (CNC (CCCCCN2C (=O) C=CC2=O) =O) =O) =O) =O) =O) [C@@H]3C4=C5C (C=6N (C5) C (=O) C7=C (C6) [C@] (CC) (O) C (=O) OC7) =NC=8C4=C (CC3) C (C) =C (F) C8

Molecular Formula

C49H51FN8O11

Molecular Weight

946.98

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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