N- (PEG3-acid) -N-bis (PEG3-amine)

This polyethylene glycol (PEG) -based linker, featuring an acid and dual amine termini, is designed for constructing PROTAC molecules. It serves as a critical bifunctional spacer to connect E3 ligase ligands with target protein binders, facilitating the development of degraders for both in vitro and in vivo research applications.