SPDP-C6-NHS ester
SPDP-C6-NHS ester is a heterobifunctional crosslinker used to construct PROTAC molecules for targeted protein degradation. It enables the conjugation of a target protein ligand to an E3 ligase recruiter, facilitating the study of protein function in both cellular and in vivo models via the ubiquitin-proteasome system.
Product Specifications
CAS Number
158913-22-5
Product Name Alternative
SPDPC6NHS ester, SPDP-C-6-NHS ester, SPDP-C6-NHS ester, SPDP C6 NHS ester, Alkyl/ether
Field of Research
Pharmacology & Drug Discovery
Purity
98.96% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.7 mM) ; DMSO:40 mg/mL (94 mM)
Smiles
O=C (ON1C (=O) CCC1=O) CCCCCNC (=O) CCSSC2=NC=CC=C2
Molecular Formula
C18H23N3O5S2
Molecular Weight
425.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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