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Tetrazine-Ph-PEG5-NHS ester

Tetrazine-Ph-PEG5-NHS ester is a heterobifunctional linker for constructing PROTAC degraders. Its tetrazine group enables bioorthogonal conjugation with TCO-modified molecules via inverse electron-demand Diels-Alder (IEDDA) click chemistry, facilitating the synthesis of compounds for targeted protein degradation studies in both cellular and animal models.

Product Specifications

CAS Number

1682653-80-0

Product Name Alternative

Alkyl/ether, PEGs, Tetrazine Ph PEG5 NHS ester, Tetrazine-PEG5-NHS ester, TetrazinePhPEG5NHS ester, Tetrazine-Ph-PEG-5-NHS ester, Tetrazine-Ph-PEG5-NHS ester

Field of Research

Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Purity

98.08% (May vary between batches)

Smiles

O=C (ON1C (=O) CCC1=O) CCOCCOCCOCCOCCOCCC (=O) NCC2=CC=C (C=C2) C=3N=NC=NN3

Molecular Formula

C27H36N6O10

Molecular Weight

604.61

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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