YM-254890

YM-254890 is a macrocyclic hexapeptide and a potent, selective inhibitor of Gαq/11 proteins. It effectively blocks ADP-induced platelet aggregation and Gq-mediated signaling pathways, making it a valuable tool for studying cardiovascular biology and GPCR mechanisms in both cellular and animal models.

Product Specifications

CAS Number

568580-02-9

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

95.00% (May vary between batches)

Smiles

CO[C@H] (C) [C@@H]1N (C) C (=O) [C@@H] (NC (=O) [C@H] (C) N (C) C (=O) [C@H] (C) NC (=O) C (=C) N (C) C (=O) [C@@H] (Cc2ccccc2) OC (=O) [C@@H] (NC (C) =O) [C@@H] (C) OC1=O) [C@H] (OC (=O) [C@@H] (NC (C) =O) [C@H] (O) C (C) C) C (C) C