(-)-5-HT2C agonist-3
Product Specifications
UNSPSC Description
(-)-5-HT2C agonist-3 (compound (–)-19) is a 5-HT2C selective agonist with Gq signaling preference, with EC50 values ??for 5-HT2 receptors of 5-HT2C: 103 nM; 5-HT2B: 570 nM; 5-HT2A: 72 nM. (-)-5-HT2C agonist-3 can be used in antipsychotic research[1].
Target Antigen
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/minus-5-ht2c-agonist-3.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
COC(C=CC=C1)=C1CNC[C@H]2[C@H](C3=C(C=CC(F)=C3)OC)C2.[H]Cl
Molecular Weight
351.84
References & Citations
[1]Guiping Zhang, et al. "Discovery of N-substituted (2-phenylcyclopropyl) methylamines as functionally selective serotonin 2C receptor agonists for potential use as antipsychotic medications." Journal of medicinal chemistry 60.14 (2017): 6273-6288.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-156532C/minus-5-HT2C-agonist-3-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-156532C/
Clinical Information
No Development Reported
CAS Number
2104810-16-2
Available Sizes
Curated Selection
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