7-O- (Amino-PEG4) -paclitaxel
7-O- (Amino-PEG4) -paclitaxel is a heterobifunctional linker used to construct PROTAC molecules, connecting a target-binding ligand to an E3 ligase recruiter. This enables targeted protein degradation via the ubiquitin-proteasome system in both cellular and in vivo research models for probing disease biology and therapeutic strategies.
Product Specifications
Field of Research
Pharmacology & Drug Discovery
Smiles
O[C@@]1 ([C@@H] (OC (C2=CC=CC=C2) =O) C3[C@@]4 (C) [C@@H] (OC (CCOCCOCCOCCOCCN) =O) C[C@@H]5[C@@]3 (OC (C) =O) CO5) C[C@H] (OC ([C@H] (O) [C@@H] (NC (C6=CC=CC=C6) =O) C7=CC=CC=C7) =O) C (C) =C ([C@@H] (OC (C) =O) C4=O) C1 (C) C
Molecular Formula
C58H72N2O19
Molecular Weight
1101.19
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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