AcLys-PABC-VC-Aur0101
AcLys-PABC-VC-Aur0101 is a cleavable drug-linker conjugate designed for constructing anti-CXCR4 antibody-drug conjugates (ADCs) . It incorporates the potent microtubule inhibitor Aur0101 and is used in research to study targeted cancer therapies, demonstrating antitumor activity in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1438851-17-2
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
[C@H] ([C@H] (C (N[C@@H] (CC1=CC=CC=C1) C2=NC=CS2) =O) C) (OC) [C@]3 (N (C (C[C@H] ([C@@H] (N (C ([C@@H] (NC (C (NC (OCC4=CC=C (NC ([C@@H] (NC ([C@@H] (NC ([C@H] (CCCCN) NC (C) =O) =O) C (C) C) =O) CCCNC (N) =O) =O) C=C4) =O) (C) C) =O) C (C) C) =O) C) [C@H] (CC) C) OC) =O) CCC3) [H]
Molecular Formula
C66H103N13O13S
Molecular Weight
1318.67
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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