Amino-PEG10-CH2-Boc

Amino-PEG10-CH2-Boc is a Boc-protected, amine-terminated polyethylene glycol linker used in constructing PROTAC molecules for targeted protein degradation. Its extended, flexible spacer is critical for connecting E3 ligase ligands to target protein binders, facilitating successful ternary complex formation and proteasomal degradation in both cellular and in vivo research models.