BIX02188
BIX02188 is a potent and selective MEK5 inhibitor. It blocks MEK5-mediated apoptosis in FLT3-ITD mutant-expressing cells and is a valuable research tool for studying oncogenic signaling in acute myeloid leukemia, applicable in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
334949-59-6
Product Name Alternative
MEK5, Apoptosis, Compound T 1744, Compound T1744, Compound T-1744
Field of Research
Cell Biology, Signal Transduction
Purity
97.66% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.42 mM) ; DMSO:30 mg/mL (72.73 mM)
Smiles
C (\NC1=CC (CN (C) C) =CC=C1) (=C\2/C=3C (NC2=O) =CC (C (N) =O) =CC3) /C4=CC=CC=C4
Molecular Formula
C25H24N4O2
Molecular Weight
412.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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