AmPEG6C2-Aur0131
AmPEG6C2-Aur0131 is a non-cleavable drug-linker conjugate for constructing anti-CXCR4 antibody-drug conjugates (ADCs) . It delivers the auristatin-based payload Aur0131, a microtubule inhibitor, to target cells. This conjugate has demonstrated potent antitumor activity in both in vitro and in vivo cancer research models.
Product Specifications
CAS Number
1650569-94-0
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
[C@H] ([C@H] (C (N[C@@H] (CC1=CC=CC=C1) C (O) =O) =O) C) (OC) [C@]2 (N (C (C[C@H] ([C@@H] (N (C ([C@@H] (NC (=O) [C@@]3 (C) N (C (CCOCCOCCOCCOCCOCCOCCN) =O) CCC3) C (C) C) =O) C) [C@H] (CC) C) OC) =O) CCC2) [H]
Molecular Formula
C54H92N6O15
Molecular Weight
1065.34
Storage Conditions
-20°C
Notes
For research use only.
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