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Biotin-PEG8-NHS ester

Biotin-PEG8-NHS ester is a heterobifunctional linker used to construct PROTAC molecules for targeted protein degradation. Its PEG spacer and reactive groups enable the conjugation of a target-binding ligand to an E3 ligase recruiter, facilitating the study of ubiquitin-proteasome system function in both cellular and in vivo models.

Product Specifications

CAS Number

2143968-03-8

Field of Research

Pharmacology & Drug Discovery

Smiles

C (CCCC (NCCOCCOCCOCCOCCOCCOCCOCCOCCC (ON1C (=O) CCC1=O) =O) =O) [C@H]2[C@@]3 ([C@] (CS2) (NC (=O) N3) [H]) [H]

Molecular Formula

C33H56N4O14S

Molecular Weight

764.88

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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