Bis-PEG23-endo-BCN

Bis-PEG23-endo-BCN is a polyethylene glycol (PEG) spacer used to construct PROTAC molecules. It connects a target-binding ligand to an E3 ligase recruiter, facilitating intracellular protein degradation via the ubiquitin-proteasome system. This linker is applied in chemical biology and drug discovery research for both in vitro and in vivo proteolysis studies.