DBCO- (PEG2-VC-PAB-MMAE) 2
This research compound features the cytotoxic payload MMAE, a potent tubulin inhibitor, conjugated via a cleavable DBCO- (PEG2-VC-PAB) 2 linker. It is a key component for constructing antibody-drug conjugates (ADCs) and is utilized in both in vitro and in vivo studies for targeted cancer therapy research.
Product Specifications
CAS Number
2259318-55-1
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
C (CCC (N (CCOCCOCCC (N[C@H] (C (N[C@H] (C (NC1=CC=C (COC (N ([C@H] (C (N[C@H] (C (N ([C@H] ([C@@H] (CC (=O) N2[C@] ([C@@H] ([C@H] (C (N[C@@H] ([C@@H] (O) C3=CC=CC=C3) C) =O) C) OC) (CCC2) [H]) OC) [C@H] (CC) C) C) =O) C (C) C) =O) C (C) C) C) =O) C=C1) =O) CCCNC (N) =O) =O) C (C) C) =O) CCOCCOCCC (N[C@H] (C (N[C@H] (C (NC4=CC=C (COC (N ([C@H] (C (N[C@H] (C (N ([C@H] ([C@@H] (CC (=O) N5[C@] ([C@@H] ([C@H] (C (N[C@@H] ([C@@H] (O) C6=CC=CC=C6) C) =O) C) OC) (CCC5) [H]) OC) [C@H] (CC) C) C) =O) C (C) C) =O) C (C) C) C) =O) C=C4) =O) CCCNC (N) =O) =O) C (C) C) =O) =O) (=O) N7C=8C (C#CC=9C (C7) =CC=CC9) =CC=CC8
Molecular Formula
C149H224N22O32
Molecular Weight
2835.5
Storage Conditions
-20°C
Notes
For research use only.
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