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DBCO- (PEG2-VC-PAB-MMAE) 2

This research compound features the cytotoxic payload MMAE, a potent tubulin inhibitor, conjugated via a cleavable DBCO- (PEG2-VC-PAB) 2 linker. It is a key component for constructing antibody-drug conjugates (ADCs) and is utilized in both in vitro and in vivo studies for targeted cancer therapy research.

Product Specifications

CAS Number

2259318-55-1

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Smiles

C (CCC (N (CCOCCOCCC (N[C@H] (C (N[C@H] (C (NC1=CC=C (COC (N ([C@H] (C (N[C@H] (C (N ([C@H] ([C@@H] (CC (=O) N2[C@] ([C@@H] ([C@H] (C (N[C@@H] ([C@@H] (O) C3=CC=CC=C3) C) =O) C) OC) (CCC2) [H]) OC) [C@H] (CC) C) C) =O) C (C) C) =O) C (C) C) C) =O) C=C1) =O) CCCNC (N) =O) =O) C (C) C) =O) CCOCCOCCC (N[C@H] (C (N[C@H] (C (NC4=CC=C (COC (N ([C@H] (C (N[C@H] (C (N ([C@H] ([C@@H] (CC (=O) N5[C@] ([C@@H] ([C@H] (C (N[C@@H] ([C@@H] (O) C6=CC=CC=C6) C) =O) C) OC) (CCC5) [H]) OC) [C@H] (CC) C) C) =O) C (C) C) =O) C (C) C) C) =O) C=C4) =O) CCCNC (N) =O) =O) C (C) C) =O) =O) (=O) N7C=8C (C#CC=9C (C7) =CC=CC9) =CC=CC8

Molecular Formula

C149H224N22O32

Molecular Weight

2835.5

Storage Conditions

-20°C

Notes

For research use only.

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