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DBCO-PEG4-VC-PAB-DMEA-PNU-159682

This ADC drug-linker conjugate combines the DBCO-PEG4-VC-PAB linker with the potent cytotoxin DMEA-PNU-159682, a metabolite of nemorubicin. It is a research tool for developing antibody-drug conjugates, applicable in both in vitro cytotoxicity assays and in vivo preclinical studies for targeted cancer therapy.

Product Specifications

CAS Number

2259318-56-2

Field of Research

Pharmacology & Drug Discovery

Smiles

O ([C@@H]1C2=C (C (O) =C3C (=C2O) C (=O) C=4C (C3=O) =CC=CC4OC) C[C@] (C (COC (N (CCN (C (OCC5=CC=C (NC ([C@@H] (NC ([C@@H] (NC (CCOCCOCCOCCOCCC (NCCC (=O) N6C=7C (C#CC=8C (C6) =CC=CC8) =CC=CC7) =O) =O) C (C) C) =O) CCCNC (N) =O) =O) C=C5) =O) C) C) =O) =O) (O) C1) [C@H]9C[C@@]%10 (N%11[C@] (O[C@@]%10 ([C@H] (C) O9) [H]) ([C@@H] (OC) OCC%11) [H]) [H]

Molecular Formula

C86H106N10O26

Molecular Weight

1695.81

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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