DM4-SMCC
DM4-SMCC is a non-cleavable drug-linker conjugate designed for constructing antibody-drug conjugates (ADCs) . It delivers the potent antitubulin agent DM4 to target cells, demonstrating antitumor activity in both in vitro cytotoxicity assays and in vivo xenograft model studies.
Product Specifications
CAS Number
1228105-52-9
Field of Research
Pharmacology & Drug Discovery
Smiles
C[C@]12[C@@] (O1) ([C@H] (C) [C@@]3 (C[C@] (O) ([C@H] (OC) /C=C/C=C (\C) /CC4=CC (N (C) C (=O) C[C@@H]2OC ([C@@H] (N (C (CCC (SC5C (=O) N (CC6CCC (C (ON7C (=O) CCC7=O) =O) CC6) C (=O) C5) (C) C) =O) C) C) =O) =C (Cl) C (OC) =C4) NC (=O) O3) [H]) [H]
Molecular Formula
C54H72ClN5O16S
Molecular Weight
1114.69
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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