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Lenalidomide-C4-NH2 hydrochloride

Lenalidomide-C4-NH2 hydrochloride is a Cereblon (CRBN) -binding ligand used to construct PROTAC degraders. This recruiting moiety, exemplified in compounds like PROTAC 24, has demonstrated potent in vitro anti-proliferative activity in acute leukemia cell models such as RS4;11 and MOLM-13.

Product Specifications

CAS Number

2435715-90-3

Field of Research

Pharmacology & Drug Discovery

Smiles

O=C (C (N (CC1=C2C=CC=C1CCCCN) C2=O) CC3) NC3=O.Cl

Molecular Formula

C17H22ClN3O3

Molecular Weight

351.83

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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