(S, R, S) -AHPC-PEG1-OTs
This compound is a VHL E3 ligase ligand-linker conjugate, synthesized from (S, R, S) -AHPC with a PEG1 spacer and a tosylate leaving group. It is a key component in constructing PROTAC molecules for targeted protein degradation, a strategy widely used in both cellular and in vivo cancer research.
Product Specifications
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Smiles
O=C ([C@H]1N (C ([C@@H] (NC (COCCOS (C2=CC=C (C) C=C2) (=O) =O) =O) C (C) (C) C) =O) C[C@H] (O) C1) NCC3=CC=C (C4=C (C) N=CS4) C=C3
Molecular Formula
C33H42N4O8S2
Molecular Weight
686.84
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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