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Thalidomide-O-amido-PEG1- (C1-​PEG) 2-C2-NH2

This compound is a cereblon-directed E3 ligase ligand-linker conjugate, featuring a thalidomide-based ligand connected via a triethylene glycol chain. It is a key component for constructing PROTACs, which are used in both in vitro and in vivo research to induce targeted protein degradation.

Product Specifications

Field of Research

Cell Biology, Pharmacology & Drug Discovery, Pharmacology & Drug Discovery; Cell Biology

Smiles

OC (C (F) (F) F) =O.O=C (NCCOCCCOCCCOCCN) COC1=CC=CC (C (N2C (CC3) C (NC3=O) =O) =O) =C1C2=O

Molecular Formula

C27H35F3N4O11

Molecular Weight

648.58

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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