Thalidomide-O-amido-PEG1- (C1-PEG) 2-C2-NH2
This compound is a cereblon-directed E3 ligase ligand-linker conjugate, featuring a thalidomide-based ligand connected via a triethylene glycol chain. It is a key component for constructing PROTACs, which are used in both in vitro and in vivo research to induce targeted protein degradation.
Product Specifications
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Pharmacology & Drug Discovery; Cell Biology
Smiles
OC (C (F) (F) F) =O.O=C (NCCOCCCOCCCOCCN) COC1=CC=CC (C (N2C (CC3) C (NC3=O) =O) =O) =C1C2=O
Molecular Formula
C27H35F3N4O11
Molecular Weight
648.58
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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