Endo-BCN-PEG4-Val-Cit-PAB-MMAE
Endo-BCN-PEG4-Val-Cit-PAB-MMAE is a cleavable linker-payload construct for synthesizing antibody-drug conjugates (ADCs) . It is widely used in ADC research for targeted cancer therapy, enabling the controlled release of the potent cytotoxin MMAE in both in vitro and in vivo experimental models.
Product Specifications
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
CC[C@@H] ([C@H] (N (C ([C@@H] (NC ([C@@H] (N (C (OCC1=CC=C (NC ([C@@H] (NC ([C@@H] (NC (CCOCCOCCOCCOCCNC (OCC2C3C2CCC#CCC3) =O) =O) C (C) C) =O) CCCNC (N) =O) =O) C=C1) =O) C) C (C) C) =O) C (C) C) =O) C) C (OC) CC (N4CCC[C@H]4[C@H] (OC) [C@H] (C (N[C@@H] ([C@@H] (O) C5=CC=CC=C5) C) =O) C) =O) C
Molecular Formula
C80H127N11O19
Molecular Weight
1546.93
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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