Fmoc-Val-Cit-PAB-Duocarmycin TM
This small molecule drug-linker conjugate features the potent cytotoxic agent Duocarmycin TM, linked via the protease-cleavable Fmoc-Val-Cit-PAB moiety. It is designed for constructing antibody-drug conjugates (ADCs) for targeted cancer therapy research, with applications in both in vitro cytotoxicity assays and in vivo preclinical efficacy studies.
Product Specifications
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
O=C (N[C@@H] (CCCNC (N) =O) C (NC1=CC=C (C=C1) COC2=CC3=C (C4=C2C=CC=C4) [C@@H] (CN3C (C5=CC6=C (C (OC) =C (C (OC) =C6) OC) N5) =O) CCl) =O) [C@@H] (NC (OCC7C8=CC=CC=C8C9=CC=CC=C79) =O) C (C) C
Molecular Formula
C58H60ClN7O10
Molecular Weight
1050.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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