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Gly-Gly-Gly-PEG4-DBCO

This product is a cleavable linker for constructing antibody-drug conjugates (ADCs), featuring a Gly-Gly-Gly tripeptide and a tetraethylene glycol (PEG4) spacer terminated with a DBCO group. It enables site-specific conjugation via strain-promoted azide-alkyne cycloaddition (SPAAC) and is suitable for developing ADCs for both in vitro and in vivo cancer research applications.

Product Specifications

CAS Number

2353409-80-8

Product Name Alternative

ADC Linker, ADC linker, ADCLinker, Cleavable, Gly Gly Gly PEG4 DBCO, GlyGlyGlyPEG4DBCO, Gly-Gly-Gly-PEG-4-DBCO, Gly-Gly-Gly-PEG4-DBCO

Solubility

Methanol:50 mg/mL (71.97 mM) ; DMSO:80 mg/mL (115.15 mM)

Smiles

O=C (NCC (=O) NCC (=O) NCCOCCOCCOCCOCCNC (=O) CCC (=O) N1C=2C=CC=CC2C#CC=3C=CC=CC3C1) CN

Molecular Formula

C35H46N6O9

Molecular Weight

694.77

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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