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VH032-PEG5-C6-Cl

VH032-PEG5-C6-Cl (HaloPROTAC 2) is a bifunctional degrader molecule that links a VHL-targeting ligand (VH032) to a chloroalkane HaloTag ligand via a PEG5-C6 linker. This compound induces targeted protein degradation of GFP-HaloTag7 fusion proteins in cellular assays, serving as a key tool for PROTAC-based research in chemical biology and target validation.

Product Specifications

CAS Number

1799506-06-1

Field of Research

Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Smiles

C ([C@@H] (NC (COCCOCCOCCOCCOCCCCCCCl) =O) [C@@] (C) (C) C) (=O) N1[C@H] (C (NCC2=CC=C (C=C2) C=3SC=NC3C) =O) C[C@@H] (O) C1

Molecular Formula

C38H59ClN4O9S

Molecular Weight

783.41

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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