Ibrutinib-biotin
Ibrutinib-biotin is a biotinylated probe derived from the potent BTK inhibitor Ibrutinib, connected via a long-chain linker. It exhibits high potency with an IC50 of 0.755-1.02 nM against BTK. This probe is widely used for in vitro and in vivo studies, including target engagement assays, cellular pull-down experiments, and proteomics research in oncology and immunology.
Product Specifications
CAS Number
1599432-18-4
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Smiles
[H][C@]12CS[C@@H] (CCCCC (=O) NCCCOCCOCCOCCCNC (=O) CCCC (=O) NCCCCN (C) CC=CC (=O) N3CCC[C@] ([H]) (C3) n3nc (-c4ccc (Oc5ccccc5) cc4) c4c (N) ncnc34) [C@@]1 ([H]) NC (=O) N2 |w:42.42|
Molecular Formula
C56H80N12O9S
Molecular Weight
1097.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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