KB02-JQ1
KB02-JQ1 is a potent and selective PROTAC degrader that specifically targets BRD4 for ubiquitin-mediated degradation by covalently engaging the E3 ligase DCAF16. This molecular glue compound exhibits enhanced stability and is a valuable chemical tool for studying BRD4 function in cancer biology and epigenetics research, both in vitro and in vivo.
Product Specifications
CAS Number
2384184-44-3
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Smiles
Cc1sc-2c (c1C) C (=N[C@@H] (CC (=O) NCCOCCOCCNC (=O) COc1ccc3N (CCCc3c1) C (=O) CCl) c1nnc (C) n-21) c1ccc (Cl) cc1 |c:8|
Molecular Formula
C38H43Cl2N7O6S
Molecular Weight
796.77
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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