KB02-SLF
KB02-SLF is a molecular glue-type PROTAC that induces nuclear FKBP12 degradation by covalently engaging the E3 ligase DCAF16. This compound is used in chemical biology and targeted protein degradation research to study FKBP12 function in both cellular and in vivo models.
Product Specifications
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
O=C ([C@H]1N (C (C (C (C) (C) CC) =O) =O) CCCC1) O[C@@H] (C2=CC=CC (NC (CCOCCOCCNC (COC3=CC4=C (N (C (CCl) =O) CCC4) C=C3) =O) =O) =C2) CCC5=CC=C (OC) C (OC) =C5
Molecular Formula
C50H65ClN4O12
Molecular Weight
949.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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